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Type
Linked Node
SIRE Susceptibility Testing
Learning ObjectivesDescribe components of SIRE kit
The BACTEC MGIT 960 susceptibility testing for Streptomycin (S), Isoniazid (I), Rifampin (R) and Ethambutol (E), called SIRE, is a rapid and qualitative method that uses critical test concentrations of the four drugs.
Components of SIRE Kit
The kit has one vial for each of the drugs (S, I, R and E) and 8 vials of the MGIT 960 SIRE Supplement.
Drugs:
Drug |
Approximate lyophilized drug per vial
|
Streptomycin (S) |
332 µg |
Isoniazid (I) |
33.2 µg |
Rifampin (R) |
332µg |
Ethambutol (E) |
1660µg |
SIRE Supplement: It differs from the MGIT Growth Supplement and contains the following:
Bovine Albumin |
50g/l
|
Dextrose |
20g/l
|
Catalase |
0.03g/l
|
Oleic Acid |
0.6g/l
|
Resource
Mycobacteriology Laboratory Manual
Assessment
Question |
Answer 1 |
Answer 2 |
Answer 3 |
Answer 4 |
Correct answer |
Correct explanation |
Page id |
Part of Pre-test |
Part of Post-te |
Which of the following is NOT a component of the SIRE kit? | Streptomycin (S) | Isoniazid (I) | Rifabutin (R) | Ethambutol (E) | Answer 3 | Components of the SIRE Kit are Streptomycin (S), Isoniazid (I), Rifampin (R), and Ethambutol (E). |
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