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NAAT Labs and their role
Learning ObjectivesDescribe NAAT labs in the context of the Lab network and the two types (CBNAAT and TruNat). Mention the roles present there (LT and MO) and the services they provide.
The National Tuberculosis (TB) Elimination Program (NTEP) has a network of Nucleic Acid Amplification Tests (NAAT) laboratories coupled with Designated Microscopy Centers (DMCs) to form the backbone of the diagnostic component of TB services.
Nucleic Acid Amplification Tests (NAAT) laboratories includes Cartridge-based NAAT (CBNAAT) and TrueNat tests. These tests detect tuberculosis as well as rifampicin resistance and are more sensitive than smear microscopy.
Functions of Nucleic Acid Amplification Test (NAAT) Laboratories:
- Acting as a hub for collection of samples from public and private health facilities (spokes)
- Universal Drug Susceptibility Testing (UDST) to rule out rifampicin resistance among confirmed TB patients
- Timely provision of NAAT test result to the TB patient, medical officer of the concerned health facility and NTEP staff for related actions
- Acting as a sample dispatch center for the Culture DST laboratory for subsequent processing of samples for first-line line probe assay (LPA) and second-line drug resistance testing utilizing second line LPA and liquid culture DST
- Recording and reporting including digitization of diagnostic process from collection to test result in NTEP Nikshay portal and Laboratory Information Management System
- Management of supplies and logistic associated with laboratory logistic (CBNAAT cartridges and TrueNAT chips) and reporting any additional requirement thereof
- Supporting the quality assurance activities undertaken by District or Intermediate Reference Laboratory under NTEP
- Support health system in carrying out special drives for key and vulnerable population and their testing directly by CBNAAT (slum population, diabetic population, smoker, malnourished people, patients of silicosis and kidney dialysis etc.)
Resources
- RNTCP Technical and Operational Guidelines for TB Control in India, 2016.
- Guidelines for Programmatic Management of Drug Resistant Tuberculosis in India, 2021.
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Approved in LT B5
Namrata Wed, 09/03/2022 - 16:54
https://cms.swasth-egurukul.in/en/page-preview/40370
Approved in LT B5