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Inbuilt Controls used in TrueNAT
Learning Objectives-
H5Content
Content
Truenat tests use Internal Quality Control to assess test validity using Internal Positive Control (IPC).
- The cartridge contains pre-loaded IPC.
- IPC is part of the full process control.
- IPC undergoes all processing steps along with specimen from extraction to amplification.
- IPC assesses the validity of the test run from sample processing to result and is illustrated in following figures (Figure 1(A) and Figure 1(B)).
Figure 1(A): Amplification of IPC in Valid Test; Source: MolBio Diagnostics Pvt. Ltd.
Figure 1(B): Invalid Test with Failure of IPC Amplification; Source: MolBio Diagnostics Pvt. Ltd.
Resources
- Truenat MTB Kit Insert.
- Trueprep AUTO Universal Cartridge Based Sample Prep Device.
- Practical Guide to Implementation of TrueNAT Tests for the Detection of TB and Rifampicin Resistance.
- MolBio Diagnostics Pvt. Ltd.
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