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H5Content
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Notes

  • Bands with intensities similar or better than Amplification Control (AC) zone are considered.
  • Not all bands of strip show same signal strength

 

Special Scenarios

  1. Both mutation probe and corresponding wild type probe are developed, represents a valid result
    • Possible reasons:
      • The tested specimen contains hetero-resistant strain
      • The tested specimen contains more than one M. tuberculosis strain (mixed infection)
  2. Resistance with wild type pattern
    • Possible reasons:
      • The tested specimen contains hetero-resistance strain; caused by mutation not covered by mutation probes
      • The tested specimen contains the wild type and resistant strain (mixed infection); mutation not covered by mutation probes
  3. Complete gene locus (all bands including Locus Control band) missing, invalid result
    • Possible reason:
      • DNA concentration below the limit of detection

 

Resources

 

 

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