Content Status

Type

Linked Node

H5Content
Content

The limitations of Second Line Probe Assay (SL-LPA) are:

 

  • It detects resistance due to mutation in gyrA, gyrB, rrs, and eis genes; resistances originating from mutations of other genes or gene regions as well as other drug resistance cannot be determined.
  • Individual strains in mixed samples cannot be differentiated, which hampers the interpretation of the test.
  • It cannot be used to monitor drug treatment, as DNA is detected from viable and non-viable bacteria.
  • The results are qualitative, the intensity of bands does not give an estimate of bacterial load in the sample.

 

 

Resources

 

 

Kindly provide your valuable feedback on the page to the link provided HERE

Content Creator

Reviewer