Content Status

Type

Linked Node

H5Content
Content

Moderate-risk TB Laboratories can:  

  1. Process specimens for inoculation on primary solid-culture media 
  2. Perform direct line-probe assays and direct Drug Sensitivity Testing (DST)

 

Essential Minimum Biosafety Measures 

  • Biological Safety Cabinets (BSCs): Class I or II
  • Ventilation: 6-12 ACH
  • Personal Protective Equipment: Laboratory gowns and gloves 
  • Laboratory design: Restricted traffic area
  • Decontamination and waste disposal
  • Procedures optimized for minimizing the generation of aerosols

 

Challenges of Moderate-risk TB Laboratories   

  • Staff may work in areas with poor ventilation and/ or poor illumination. 
  • BSCs may be poorly maintained and not certified or not be properly ducted.
  • Careless manipulation of specimens may lead to aerosolization.
  • Specimen containers may break or leak during centrifuging.
  • Adequate warnings of biohazards may be lacking, and information on who should be contacted during an emergency may be inadequate.
  • Cooling or heating systems may not work properly.

 

Resources 

 

 

Kindly provide your valuable feedback on the page to the link provided HERE
 

Content Creator

Reviewer