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Additional monitoring is recommended for pregnant women managed with a shorter/ longer oral Multidrug-resistant TB (MDR-TB) regimen including foetal and neonatal monitoring.

Table: Additional Monitoring during Pregnancy & Lactation in Women with Shorter/ Longer Oral MDR-TB Regimen
INVESTIGATION INDICATION / FREQUENCY 
Basal Thyroid Stimulating Hormone (TSH) in Pre-treatment Evaluation (PTE)

TSH Deranged in PTE - Monthly

TSH Normal in PTE- Quarterly 

Baseline investigations at birth (Complete Blood Count (CBC) and TSH) In case Para Aminosalicylic Acid (PAS), Ethionamide (Eto) or Linezolid (Lzd) is given (which causes hypothyroidism or myelosuppression) and a newborn who has been exposed to a cocktail of drugs.
An Ultrasonography (USG) foetal anomalies scan  18 weeks 
USG growth scan  32 weeks 
Frequent Electrocardiogram (ECG), serum electrolytes and CBC  As and when clinically indicated.
Antenatal care registration and regular Obstetric/ Gynaecology (Ob/Gy) examination As per the regular schedule of Ante-natal care (ANC) visits

 

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