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All women of childbearing age who are awaiting results of the Culture and Drug Susceptibility Test (C&DST), as well as those receiving Drug-resistant TB (DR-TB) treatment, should be advised and counselled intensively to use birth control measures because of the potential risk to both the mother and the foetus.​

  • It should be noted that oral contraceptives might have decreased efficacy due to vomiting and drug interactions with DR-TB drugs (use of Rifampicin in mono/poly resistant TB).​
  • Contraception methods that can be used during DR-TB treatment, based on individual preference and eligibility are: ​
    • Barrier methods (e.g., condoms/ diaphragms)​, intrauterine devices (e.g., CuT), Depot medroxyprogesterone (Depo-provera)​.
  • In women, the Isoniazid (H) mono/poly DR-TB regimen may be started or continued safely, except that care should be taken while using oral contraceptives. ​
  • A woman on oral contraception, while receiving rifampicin treatment may choose between two options following consultation with a physician: ​
    • Use of an oral contraceptive pill containing a higher dose of oestrogen (50 μg)​
    • Use of another form of contraception. 

 

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