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Type
Linked Node
Regimen for TPT
Learning ObjectivesThe learner will be able to discuss the regimens used for TPT.
The following TPT treatment options are recommended under NTEP once active TB has been ruled out:
6H |
3HP |
|
---|---|---|
Medicines |
Isoniazid |
Isoniazid + rifapentine |
Duration (months) |
6 |
3 |
Interval |
Daily |
Weekly |
Doses |
182 |
12 |
Pregnant women |
Safe for use |
Not Known |
Post-treatment TPT for PLHIV: In patients previously treated for TB, post-treatment TPT has been considered in view of the 5-7 times higher risk of recurrence of TB among PLHIV and nearly 90% of these due to re-infection. Thus, all CLHIV/PLHIV who had successfully completed treatment for TB disease earlier should receive a course of TPT after completing treatment of TB.
Resources
-
Guideline for Programmatic Management of Tuberculosis Preventive Treatment in India
-
Latent TB Infection : Updated and Consolidated Guidelines for Programmatic Management, WHO, 2018
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