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Biochemical Tests for MTB
Learning ObjectivesList all biochemical tests for MTB used in CDST laboratories
Biochemical Tests for MTB
An experienced laboratory technologist may make the presumptive diagnosis of tuberculosis on the basis of the morphological characteristics of tubercle bacilli, but it is best to do confirmatory tests.
Unfortunately, there is no completely reliable single test that will differentiate M. tuberculosis from other mycobacteria. Nevertheless, the following tests, when used in combination with the characteristics, will enable the precise identification of > 95% of M.tuberculosis strains:
1) Susceptibility to p-nitrobenzoic acid (PNB)
2) Niacin test
3) Catalase activity at 68°C & pH 7.
Of these, the PNB test can be included along with the drug susceptibility test.
Resource
Assessment
Question 1 |
Answer 1 |
Answer 2 |
Answer 3 |
Answer 4 |
Correct Answer |
Correct Explanation |
Page id |
Part of Pre-Test |
Part of Post-Test |
Biochemical tests differentiate M. tuberculosis from other mycobacteria. |
True |
False |
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True |
PNB, Niacin and Catalase tests are used to differentiate M. tuberculosis from other mycobacteria. |
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Yes |
Yes |
Question 2 |
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PNB test can be included along with the drug susceptibility test. |
True |
False |
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True |
PNB test can be included along with the drug susceptibility test. |
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Yes |
Yes |
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