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Tuberculous lymphadenitis<\/strong><\/span> is a local manifestation of the systemic disease. <\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span>TB LN may represent a spread of infection from the tonsils, adenoids, sino-nasal or osteomyelitis of the ethmoid bone. <\/li>\n\t
It may occur during primary tuberculous infection or as a result of reactivation of dormant foci or direct extension from a contiguous focus<\/span><\/strong><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/li>\n<\/ul>\n"},"subContentId":"d537e932-ee33-4b12-8ae9-eb41badd932b","metadata":{"contentType":"Text","license":"U","title":"Untitled Text"}},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""},{"x":4.357298474945534,"y":32.39740820734341,"width":16.33986928104575,"height":8.639308855291576,"action":{"library":"H5P.AdvancedText 1.1","params":{"text":"
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Portal of entry :<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/strong><\/li>\n<\/ul>\n"},"subContentId":"3c08f2c6-7112-444c-a94e-d72192aa4d91","metadata":{"contentType":"Text","license":"U","title":"Untitled Text"}},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""},{"x":9.803921568627452,"y":45.44643628509719,"width":84.9673202614379,"height":17.278617710583152,"action":{"library":"H5P.AdvancedText 1.1","params":{"text":"
1. Via respiratory tract <\/strong>- haematogenous and lymphatic dissemination. Hilar and mediastinal lymph nodes are involved initially, and rest follows<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/p>\n"},"subContentId":"de0050fd-749f-4f42-a3d0-771a54e9ce0e","metadata":{"contentType":"Text","license":"U","title":"Untitled Text"}},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""},{"x":9.803921568627452,"y":60.60107991360692,"width":82.78867102396515,"height":10.799136069114471,"action":{"library":"H5P.AdvancedText 1.1","params":{"text":"
2. <\/span><\/span><\/span><\/span>Via tonsil - spreads via the lymphatics to the draining cervical lymph nodes <\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/p>\n"},"metadata":{"contentType":"Text","license":"U","title":"Untitled Text"},"subContentId":"362277a3-281d-4fa8-9102-be60eda4f83d"},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""},{"x":32.6797385620915,"y":90.71274298056156,"width":65.359477124183,"height":5.183585313174946,"action":{"library":"H5P.AdvancedText 1.1","params":{"text":"
Kent DC. tuberculous lymphadenitis: not a localized disease process. Am J Med sci. 1967;254:866-874. <\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/em><\/p>\n"},"subContentId":"5e63e6fa-ab85-44f6-930c-a5b53ad29bce","metadata":{"contentType":"Text","license":"U","title":"Untitled Text"}},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""},{"x":9.803921568627452,"y":73.43412526997841,"width":82.78867102396515,"height":10.799136069114471,"action":{"library":"H5P.AdvancedText 1.1","params":{"text":"
3. <\/span><\/span><\/span><\/span><\/span><\/span><\/span>Abdominal tuberculous lymphadenopathy may occur via swallowing of sputum or milk infected with M. tuberculosis\/M. bovis<\/p>\n"},"metadata":{"contentType":"Text","license":"U","title":"Untitled Text"},"subContentId":"3e5df5b1-50c1-4532-a50b-1ec5879bfe93"},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""}],"slideBackgroundSelector":{}},{"elements":[{"x":49.01960784313726,"y":28.077753779697623,"width":48.80174291938998,"height":53.99568034557235,"action":{"library":"H5P.Image 1.1","params":{"decorative":false,"contentName":"Image","file":{"path":"images\/file-6490322bdfaa4.png","mime":"image\/png","copyright":{"license":"U"},"width":980,"height":551}},"subContentId":"87e6e1e1-8655-41de-826b-23268c7b569c","metadata":{"contentType":"Image","license":"U","title":"Untitled Image"}},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""},{"x":4.357298474945534,"y":6.479481641468682,"width":90.41394335511983,"height":15.11879049676026,"action":{"library":"H5P.AdvancedText 1.1","params":{"text":"
In the initial stage of superficial lymph node involvement, progressive multiplication of M. tuberculosis occurs.<\/span><\/strong> The onset of delayed hypersensitivity is accompanied by marked hyperaemia, swelling, necrosis and caseation of the centre of the nodes. <\/p>\n"},"subContentId":"fdaa87b8-7964-4a04-902b-3264a52062f9","metadata":{"contentType":"Text","license":"U","title":"Untitled Text"}},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""},{"x":3.2679738562091507,"y":19.510431965442763,"width":44.66230936819172,"height":77.7537796976242,"action":{"library":"H5P.AdvancedText 1.1","params":{"text":"
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This can be followed by inflammation, progressive swelling and matting<\/span><\/strong> with other nodes within a group. <\/p>\n\t<\/li>\n\t
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Adhesion to the adjacent skin may result in induration and purplish discolouration<\/span><\/strong>. <\/p>\n\t<\/li>\n\t
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The centre of the enlarging gland becomes soft and caseous material may rupture into surrounding tissue <\/span><\/strong>or through the skin with sinus formation. <\/p>\n\t<\/li>\n\t
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Tuberculous mediastinal lymphadenitis may enlarge and cause compression of major blood vessels, phrenic or recurrent laryngeal nerves or cause erosion of bronchus<\/span><\/strong>.<\/p>\n\t<\/li>\n<\/ul>\n"},"subContentId":"7be3c5dc-4061-4a90-bc6a-812abf015f64","metadata":{"contentType":"Text","license":"U","title":"Untitled Text"}},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""}],"slideBackgroundSelector":{}},{"elements":[{"x":5.446623093681917,"y":8.639308855291576,"width":89.32461873638344,"height":84.23326133909288,"action":{"library":"H5P.AdvancedText 1.1","params":{"text":"
Jones and Campbell classified peripheral tuberculous lymph nodes into following five stages:<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/p>\n\n
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Stage 1<\/span><\/span>: Reactive lymphadenitis - enlarged, firm, mobile, discrete nodes showing non-specific reactive hyperplasia<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/p>\n\t<\/li>\n\t
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Stage 2: <\/span><\/span>Periadenitis -large rubbery nodes fixed to surrounding tissue<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/p>\n\t<\/li>\n\t
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Stage 3: <\/span><\/span>Cold abscess -central softening due to abscess formation<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/p>\n\t<\/li>\n\t
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Stage 4: <\/span><\/span>Collar-stud abscess formation<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/p>\n\t<\/li>\n\t
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Stage 5: <\/span><\/span>Sinus tract formation<\/span><\/span><\/span><\/span><\/span><\/span><\/p>\n\t<\/li>\n<\/ul>\n"},"subContentId":"800eee41-739d-4854-b286-543f7e5e8c91","metadata":{"contentType":"Text","license":"U","title":"Untitled Text"}},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""},{"x":44.66230936819172,"y":84.23326133909288,"width":51.19825708061002,"height":12.958963282937365,"action":{"library":"H5P.AdvancedText 1.1","params":{"text":"
Jones Pg, Campbell PE. tuberculous lymphadenitis in childhood: the significance of anonymous mycobacteria. Br J surg. 1962;50:302- 314<\/em><\/span><\/p>\n"},"subContentId":"82115a0d-7257-48d9-be3b-35836e45a3fd","metadata":{"contentType":"Text","license":"U","title":"Untitled Text"}},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""}],"slideBackgroundSelector":{}}],"keywordListEnabled":true,"globalBackgroundSelector":{},"keywordListAlwaysShow":false,"keywordListAutoHide":false,"keywordListOpacity":90},"override":{"activeSurface":false,"hideSummarySlide":false,"summarySlideSolutionButton":true,"summarySlideRetryButton":true,"enablePrintButton":false,"social":{"showFacebookShare":false,"facebookShare":{"url":"@currentpageurl","quote":"I scored @score out of @maxScore on a task at @currentpageurl."},"showTwitterShare":false,"twitterShare":{"statement":"I scored @score out of @maxScore on a task at @currentpageurl.","url":"@currentpageurl","hashtags":"h5p, course"},"showGoogleShare":false,"googleShareUrl":"@currentpageurl"}},"l10n":{"slide":"Slide","score":"Score","yourScore":"Your Score","maxScore":"Max Score","total":"Total","totalScore":"Total Score","showSolutions":"Show solutions","retry":"Retry","exportAnswers":"Export text","hideKeywords":"Hide sidebar navigation menu","showKeywords":"Show sidebar navigation menu","fullscreen":"Fullscreen","exitFullscreen":"Exit fullscreen","prevSlide":"Previous slide","nextSlide":"Next slide","currentSlide":"Current slide","lastSlide":"Last slide","solutionModeTitle":"Exit solution mode","solutionModeText":"Solution Mode","summaryMultipleTaskText":"Multiple tasks","scoreMessage":"You achieved:","shareFacebook":"Share on Facebook","shareTwitter":"Share on Twitter","shareGoogle":"Share on Google+","summary":"Summary","solutionsButtonTitle":"Show comments","printTitle":"Print","printIngress":"How would you like to print this presentation?","printAllSlides":"Print all slides","printCurrentSlide":"Print current slide","noTitle":"No title","accessibilitySlideNavigationExplanation":"Use left and right arrow to change slide in that direction whenever canvas is selected.","accessibilityCanvasLabel":"Presentation canvas. Use left and right arrow to move between slides.","accessibilityProgressBarLabel":"Choose slide to display","containsNotCompleted":"@slideName contains not completed interaction","containsCompleted":"@slideName contains completed interaction","slideCount":"Slide @index of @total","containsOnlyCorrect":"@slideName only has correct answers","containsIncorrectAnswers":"@slideName has incorrect answers","shareResult":"Share Result","accessibilityTotalScore":"You got @score of @maxScore points in total","accessibilityEnteredFullscreen":"Entered fullscreen","accessibilityExitedFullscreen":"Exited fullscreen","confirmDialogHeader":"Submit your answers","confirmDialogText":"This will submit your results, do you want to continue?","confirmDialogConfirmText":"Submit and see results","slideshowNavigationLabel":"Slideshow navigation"}}

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Pathogenesis of LNTB

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Pathogenesis of LNTB

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