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Microbiological diagnosis \u2013 Microscopy<\/strong><\/p>\n"},"subContentId":"70ff6272-7d8b-4855-bc46-1a57965d4a3e","metadata":{"contentType":"Text","license":"U","title":"Untitled Text"}},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""},{"x":13.071895424836601,"y":21.598272138228943,"width":75.16339869281046,"height":60.47516198704104,"action":{"library":"H5P.Table 1.1","params":{"text":"

\n\n\t\n\t\t\n\t\t\t\n\t\t\t\n\t\t\t
Method<\/span><\/td>\n\t\t\t Merits<\/span><\/td>\n\t\t\t Limitations<\/span><\/td>\n\t\t<\/tr>\n\t\t
ZN stain<\/td>\n\t\t\t \n\t\t\t1. To be performed on all cases\n\n\t\t\t
\n\t\t\t2. Easily available\n\n\t\t\t
\n\t\t\t3. Specificity > 90%\n\t\t\t<\/td>\n\t\t\t \n\t\t\t1. Sensitivity < 50 %\n\n\t\t\t
\n\t\t\t2. Negative result don\u2019t rule out TB\n\n\t\t\t
\n\t\t\t3. Not used for response monitoring\n\t\t\t<\/td>\n\t\t<\/tr>\n\t\t
\n\t\t\tFluorescence Microscopy\n\n\t\t\t(LED-FM)\n\n\t\t\t \n\t\t\t<\/td>\n\t\t\t \n\t\t\t
Increased of speed and <\/div>\n\n\t\t\t
ease of screening, and reduces observer fatigue<\/div>\n\n\t\t\t
<\/div>\n\t\t\t<\/td>\n\t\t\t
<\/td>\n\t\t<\/tr>\n\t<\/tbody>\n<\/table>\n\n
<\/div>\n<\/div>\n"},"subContentId":"adf7e7a3-0a78-40d7-80fc-5fd2135f5efd","metadata":{"contentType":"Table","license":"U","title":"Untitled Table"}},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""},{"x":22.875816993464053,"y":84.23326133909288,"width":76.25272331154684,"height":10.799136069114471,"action":{"library":"H5P.AdvancedText 1.1","params":{"text":"
A Comparative Study of Fluorescence Microscopy with Ziehl<\/span><\/span><\/span><\/span><\/span> Neelsen Staining for Detection of Acid Fast Bacilli in Lymph Node Aspirates , Supreet Kaur Kalra , International Journal of Science and Research (IJSR), 2018 <\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/p>\n"},"subContentId":"59f44f40-77d9-4169-9470-ec0ab9a408ba","metadata":{"contentType":"Text","license":"U","title":"Untitled Text"}},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""}],"slideBackgroundSelector":{}},{"elements":[{"x":5.446623093681917,"y":8.675313174946005,"width":62.091503267973856,"height":8.639308855291576,"action":{"library":"H5P.AdvancedText 1.1","params":{"text":"
Microbiological diagnosis- Molecular Method (GeneXpert MTB\/RIF)<\/strong><\/p>\n"},"subContentId":"0e9acccf-971b-4a5d-b263-b3a0e91849b7","metadata":{"contentType":"Text","license":"U","title":"Untitled Text"}},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""},{"x":5.446623093681917,"y":28.077753779697623,"width":92.5925925925926,"height":45.35637149028078,"action":{"library":"H5P.Table 1.1","params":{"text":"
\n\t\n\t\t\n\t\t\t\n\t\t\t
Merits<\/strong><\/span><\/td>\n\t\t\t Limitations <\/strong><\/span><\/td>\n\t\t\t Comments <\/strong><\/span><\/td>\n\t\t<\/tr>\n\t\t
\n\t\t\t
<\/div>\n\n\t\t\t
1. Rapid , automated and easy<\/div>\n\n\t\t\t
to interpret
\n\t\t\t2. Sensitivity%- 84.9 (72-92)
\n\t\t\t3. Specificity%- 92.5 (80-97)
\n\t\t\t4. May identify Rifampicin resistance<\/div>\n\t\t\t<\/td>\n\t\t\t
\n\t\t\t
1. Negative test does not rule<\/div>\n\n\t\t\t
out LNTB
\n\t\t\t2. Cannot be used to monitor<\/div>\n\n\t\t\t
response to therapy<\/div>\n\t\t\t<\/td>\n\t\t\t
\n\t\t\t
May be preferred over conventional<\/div>\n\n\t\t\t
tests(microscopy, culture or<\/div>\n\n\t\t\t
histopathology) in a limited<\/div>\n\n\t\t\t
amount of sample<\/div>\n\t\t\t<\/td>\n\t\t<\/tr>\n\t<\/tbody>\n<\/table>\n\n
<\/div>\n"},"subContentId":"cc49f18f-58cc-4d77-9a6c-d73a513ed621","metadata":{"contentType":"Table","license":"U","title":"Untitled Table"}},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""},{"x":44.66230936819172,"y":86.39308855291577,"width":52.287581699346404,"height":10.799136069114471,"action":{"library":"H5P.AdvancedText 1.1","params":{"text":"
Xpert MTB\/RIF assay for the diagnosis of pulmonary and extrapulmonary TB in adults and children Policy update, WHO , 2013 <\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/p>\n"},"subContentId":"a85c6c5c-8931-4cd3-b520-6bc00cb370ac","metadata":{"contentType":"Text","license":"U","title":"Untitled Text"}},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""}],"slideBackgroundSelector":{}},{"elements":[{"x":5.446623093681917,"y":8.675313174946005,"width":62.091503267973856,"height":8.639308855291576,"action":{"library":"H5P.AdvancedText 1.1","params":{"text":"
Microbiological diagnosis- Culture<\/strong><\/p>\n"},"subContentId":"5e202dc5-0df9-4868-9f2c-18a58d0265cc","metadata":{"contentType":"Text","license":"U","title":"Untitled Text"}},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""},{"x":6.5359477124183005,"y":28.077753779697623,"width":87.14596949891067,"height":43.196544276457885,"action":{"library":"H5P.Table 1.1","params":{"text":"
\n\t\n\t\t\n\t\t\t\n\t\t\t
Methods<\/strong><\/span><\/td>\n\t\t\t Merits<\/strong><\/span><\/td>\n\t\t\t Limitations<\/strong><\/span><\/td>\n\t\t<\/tr>\n\t\t
\n\t\t\t
<\/div>\n\n\t\t\t
1. Lowenstein-Jensen (LJ) medium
\n\t\t\t2. Automated BACTEC systems<\/div>\n\n\t\t\t
(MGIT 960)
\n\t\t\t <\/div>\n\n\t\t\t
<\/div>\n\t\t\t<\/td>\n\t\t\t
\n\t\t\t
<\/div>\n\n\t\t\t
1. Gold standard
\n\t\t\t2. To be performed in all cases
\n\t\t\t3. Permits drug susceptibility testing
\n\t\t\t4. High specificity<\/div>\n\t\t\t<\/td>\n\t\t\t
\n\t\t\t
1. Long incubation period
\n\t\t\t2. Low sensitivity<\/div>\n\t\t\t<\/td>\n\t\t<\/tr>\n\t<\/tbody>\n<\/table>\n\n
<\/div>\n"},"subContentId":"5535d19f-f28c-43c5-96b1-02505ec3f8d9","metadata":{"contentType":"Table","license":"U","title":"Untitled Table"}},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""},{"x":25.05446623093682,"y":84.23326133909288,"width":72.98474945533769,"height":10.799136069114471,"action":{"library":"H5P.AdvancedText 1.1","params":{"text":"
European Journal of Clinical Microbiology & Infectious Diseases June 2014, Volume 33, Performance of solid and liquid culture media for the detection of Mycobacterium tuberculosis in clinical materials: meta-analysis of recent studies<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/p>\n"},"subContentId":"8371aff0-f009-4e03-94e3-060507d0b84a","metadata":{"contentType":"Text","license":"U","title":"Untitled Text"}},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""}],"slideBackgroundSelector":{}}],"keywordListEnabled":true,"globalBackgroundSelector":{},"keywordListAlwaysShow":false,"keywordListAutoHide":false,"keywordListOpacity":90},"override":{"activeSurface":false,"hideSummarySlide":false,"summarySlideSolutionButton":true,"summarySlideRetryButton":true,"enablePrintButton":false,"social":{"showFacebookShare":false,"facebookShare":{"url":"@currentpageurl","quote":"I scored @score out of @maxScore on a task at @currentpageurl."},"showTwitterShare":false,"twitterShare":{"statement":"I scored @score out of @maxScore on a task at @currentpageurl.","url":"@currentpageurl","hashtags":"h5p, course"},"showGoogleShare":false,"googleShareUrl":"@currentpageurl"}},"l10n":{"slide":"Slide","score":"Score","yourScore":"Your Score","maxScore":"Max Score","total":"Total","totalScore":"Total Score","showSolutions":"Show solutions","retry":"Retry","exportAnswers":"Export text","hideKeywords":"Hide sidebar navigation menu","showKeywords":"Show sidebar navigation menu","fullscreen":"Fullscreen","exitFullscreen":"Exit fullscreen","prevSlide":"Previous slide","nextSlide":"Next slide","currentSlide":"Current slide","lastSlide":"Last slide","solutionModeTitle":"Exit solution mode","solutionModeText":"Solution Mode","summaryMultipleTaskText":"Multiple tasks","scoreMessage":"You achieved:","shareFacebook":"Share on Facebook","shareTwitter":"Share on Twitter","shareGoogle":"Share on Google+","summary":"Summary","solutionsButtonTitle":"Show comments","printTitle":"Print","printIngress":"How would you like to print this presentation?","printAllSlides":"Print all slides","printCurrentSlide":"Print current slide","noTitle":"No title","accessibilitySlideNavigationExplanation":"Use left and right arrow to change slide in that direction whenever canvas is selected.","accessibilityCanvasLabel":"Presentation canvas. Use left and right arrow to move between slides.","accessibilityProgressBarLabel":"Choose slide to display","containsNotCompleted":"@slideName contains not completed interaction","containsCompleted":"@slideName contains completed interaction","slideCount":"Slide @index of @total","containsOnlyCorrect":"@slideName only has correct answers","containsIncorrectAnswers":"@slideName has incorrect answers","shareResult":"Share Result","accessibilityTotalScore":"You got @score of @maxScore points in total","accessibilityEnteredFullscreen":"Entered fullscreen","accessibilityExitedFullscreen":"Exited fullscreen","confirmDialogHeader":"Submit your answers","confirmDialogText":"This will submit your results, do you want to continue?","confirmDialogConfirmText":"Submit and see results","slideshowNavigationLabel":"Slideshow navigation"}}

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Microbiological confirmation in LNTB

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Microbiological confirmation in LNTB

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