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Clinical Presentation - TB meningitis (TBM) <\/span><\/span><\/strong><\/span><\/p>\n"},"metadata":{"contentType":"Text","license":"U","title":"Untitled Text"},"subContentId":"af483fa6-fbb9-42cf-9a14-08b67385c7e8"},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""},{"x":4.3544662309368185,"y":17.312354211663067,"width":55.55555555555556,"height":34.557235421166304,"action":{"library":"H5P.AdvancedText 1.1","params":{"text":"

\n\t
\n\t
Leptomeningeal form is the most common form<\/p>\n\t<\/li>\n\t
\n\t
Symptoms depending on site of involvement and macroscopic complications<\/p>\n\t<\/li>\n\t
\n\t
Most common symptoms \u2013 Fever, headache, lethargy    <\/p>\n\t<\/li>\n<\/ul>\n"},"subContentId":"21e6011a-aff7-49ac-b50b-a6ba445f99a9","metadata":{"contentType":"Text","license":"U","title":"Untitled Text"}},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""},{"x":62.091503267973856,"y":19.43844492440605,"width":33.769063180827885,"height":69.11447084233261,"action":{"library":"H5P.Table 1.1","params":{"text":"
\n\n\t\n\t\t\n\t\t\t\n\t\t\t\n\t\t\t\n\t\t\t\n\t\t\t\n\t\t\t\n\t\t\t\n\t\t\t\n\t\t\t\n\t\t\t\n\t\t\t
Symptoms <\/strong><\/span><\/td>\n\t\t\t Frequency<\/strong><\/span><\/td>\n\t\t<\/tr>\n\t\t
Vomiting<\/td>\n\t\t\t 69.7<\/td>\n\t\t<\/tr>\n\t\t
Altered sensorium   <\/td>\n\t\t\t 69.2<\/td>\n\t\t<\/tr>\n\t\t
Anorexia<\/td>\n\t\t\t 57.1<\/td>\n\t\t<\/tr>\n\t\t
Seizures<\/td>\n\t\t\t 34.4<\/td>\n\t\t<\/tr>\n\t\t
Vision impairment<\/td>\n\t\t\t 21.2<\/td>\n\t\t<\/tr>\n\t\t
Meningeal signs<\/td>\n\t\t\t 81.8<\/td>\n\t\t<\/tr>\n\t\t
Papilledema<\/td>\n\t\t\t 48.5<\/td>\n\t\t<\/tr>\n\t\t
Cranial nerves<\/td>\n\t\t\t \n\t\t\t
47(>=1 cranial<\/div>\n\n\t\t\t
nerve palsy)<\/div>\n\t\t\t<\/td>\n\t\t<\/tr>\n\t\t
Optic atrophy<\/td>\n\t\t\t 14.6<\/td>\n\t\t<\/tr>\n\t\t
Extraneural TB<\/td>\n\t\t\t 14.1<\/td>\n\t\t<\/tr>\n\t<\/tbody>\n<\/table>\n\n
<\/div>\n<\/div>\n"},"subContentId":"9b1b17eb-c831-4197-a87b-a604d7580c67","metadata":{"contentType":"Table","license":"U","title":"Untitled Table"}},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""},{"x":4.357298474945534,"y":90.71274298056156,"width":81.69934640522877,"height":6.479481641468682,"action":{"library":"H5P.AdvancedText 1.1","params":{"text":"
   Goyal, Vinay, et al. \u201cPractice Trends in Treating CNS TB and Outcomes at a Tertiary Care Hospital: A Cohort Study of 244 Cases.2019<\/span><\/p>\n"},"subContentId":"ee199d32-ea76-46d7-b01e-cfaf50007dfb","metadata":{"contentType":"Text","license":"U","title":"Untitled Text"}},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""}],"slideBackgroundSelector":{}},{"elements":[{"x":4.357298474945534,"y":8.639308855291576,"width":40.30501089324619,"height":10.799136069114471,"action":{"library":"H5P.AdvancedText 1.1","params":{"text":"
Differential Diagnosis of TB Meningitis<\/span><\/span><\/strong><\/span><\/p>\n"},"subContentId":"7fd1dc81-a197-4646-b585-eaad24a4f411","metadata":{"contentType":"Text","license":"U","title":"Untitled Text"}},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""},{"x":5.446623093681917,"y":17.278617710583152,"width":51.19825708061002,"height":73.43412526997841,"action":{"library":"H5P.AdvancedText 1.1","params":{"text":"
\n\t
\n\t
Partially treated bacterial meningitis<\/p>\n\t<\/li>\n\t
\n\t
Fungal (Cryptococcal) meningitis*<\/p>\n\t<\/li>\n\t
\n\t
Viral meningoencephalitis<\/p>\n\t<\/li>\n\t
\n\t
Carcinomatous meningitis<\/p>\n\t<\/li>\n\t
\n\t
Neuro-sarcoidosis<\/p>\n\t<\/li>\n\t
\n\t
Neurosyphilis<\/p>\n\t<\/li>\n\t
\n\t
Uncommon: Lyme\u2019s disease, Brucellosis<\/p>\n\t<\/li>\n<\/ul>\n"},"subContentId":"a5efa0d6-63e5-4f2e-b138-20a75a29ea52","metadata":{"contentType":"Text","license":"U","title":"Untitled Text"}},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""},{"x":5.446623093681917,"y":88.55291576673866,"width":65.359477124183,"height":6.479481641468682,"action":{"library":"H5P.AdvancedText 1.1","params":{"text":"
* Important to rule out cryptococcal meningitis - implications with respect to steroids<\/span><\/em><\/p>\n"},"subContentId":"b9dcd3ce-4a28-4e11-9ca7-a1d7e04f01e0","metadata":{"contentType":"Text","license":"U","title":"Untitled Text"}},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""}],"slideBackgroundSelector":{}},{"elements":[{"x":4.357298474945534,"y":10.799136069114471,"width":62.091503267973856,"height":8.639308855291576,"action":{"library":"H5P.AdvancedText 1.1","params":{"text":"
Clinical Presentation - CNS Tuberculoma\/abscess<\/span><\/span><\/strong><\/span><\/p>\n"},"subContentId":"12fbd60a-5780-4581-93ff-5680b796cc66","metadata":{"contentType":"Text","license":"U","title":"Untitled Text"}},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""},{"x":5.443790849673203,"y":17.312354211663067,"width":89.32461873638344,"height":71.27429805615552,"action":{"library":"H5P.AdvancedText 1.1","params":{"text":"
\n\t
\n\t
It is less common than TBM ( about 40%) and has lower morbidity and mortality<\/p>\n\t<\/li>\n\t
\n\t
It can arise anywhere in brain or spinal cord<\/p>\n\t<\/li>\n\t
\n\t
It may present as <\/p>\n\t<\/li>\n<\/ul>\n\n
a) Asymptomatic
\n b) Focal seizures
\n c) Mass lesion causing focal neurological deficits<\/p>\n\n
\n\t
\n\t
Presumptive CNS tuberculoma: Any patient presenting with seizures, headache, fever or focal neurological deficits with neuroimaging features consistent with a mass lesion of inflammatory nature.<\/p>\n\t<\/li>\n<\/ul>\n"},"subContentId":"e7aaf2d1-8b91-489d-a495-022e9b6c9bd4","metadata":{"contentType":"Text","license":"U","title":"Untitled Text"}},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""},{"x":4.357298474945534,"y":84.23326133909288,"width":76.25272331154684,"height":10.799136069114471,"action":{"library":"H5P.AdvancedText 1.1","params":{"text":"
Index TB Guidelines 2016;
\nGoyal, Vinay, et al. \u201cPractice Trends in Treating CNS TB and Outcomes at a Tertiary Care Hospital: A Cohort Study of 244 Cases.2019<\/span><\/p>\n"},"subContentId":"9cfaad21-fc1f-493d-b199-d48e4f1b09a0","metadata":{"contentType":"Text","license":"U","title":"Untitled Text"}},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""}],"slideBackgroundSelector":{}}],"keywordListEnabled":true,"globalBackgroundSelector":{},"keywordListAlwaysShow":false,"keywordListAutoHide":false,"keywordListOpacity":90},"override":{"activeSurface":false,"hideSummarySlide":false,"summarySlideSolutionButton":true,"summarySlideRetryButton":true,"enablePrintButton":false,"social":{"showFacebookShare":false,"facebookShare":{"url":"@currentpageurl","quote":"I scored @score out of @maxScore on a task at @currentpageurl."},"showTwitterShare":false,"twitterShare":{"statement":"I scored @score out of @maxScore on a task at @currentpageurl.","url":"@currentpageurl","hashtags":"h5p, course"},"showGoogleShare":false,"googleShareUrl":"@currentpageurl"}},"l10n":{"slide":"Slide","score":"Score","yourScore":"Your Score","maxScore":"Max Score","total":"Total","totalScore":"Total Score","showSolutions":"Show solutions","retry":"Retry","exportAnswers":"Export text","hideKeywords":"Hide sidebar navigation menu","showKeywords":"Show sidebar navigation menu","fullscreen":"Fullscreen","exitFullscreen":"Exit fullscreen","prevSlide":"Previous slide","nextSlide":"Next slide","currentSlide":"Current slide","lastSlide":"Last slide","solutionModeTitle":"Exit solution mode","solutionModeText":"Solution Mode","summaryMultipleTaskText":"Multiple tasks","scoreMessage":"You achieved:","shareFacebook":"Share on Facebook","shareTwitter":"Share on Twitter","shareGoogle":"Share on Google+","summary":"Summary","solutionsButtonTitle":"Show comments","printTitle":"Print","printIngress":"How would you like to print this presentation?","printAllSlides":"Print all slides","printCurrentSlide":"Print current slide","noTitle":"No title","accessibilitySlideNavigationExplanation":"Use left and right arrow to change slide in that direction whenever canvas is selected.","accessibilityCanvasLabel":"Presentation canvas. Use left and right arrow to move between slides.","accessibilityProgressBarLabel":"Choose slide to display","containsNotCompleted":"@slideName contains not completed interaction","containsCompleted":"@slideName contains completed interaction","slideCount":"Slide @index of @total","containsOnlyCorrect":"@slideName only has correct answers","containsIncorrectAnswers":"@slideName has incorrect answers","shareResult":"Share Result","accessibilityTotalScore":"You got @score of @maxScore points in total","accessibilityEnteredFullscreen":"Entered fullscreen","accessibilityExitedFullscreen":"Exited fullscreen","confirmDialogHeader":"Submit your answers","confirmDialogText":"This will submit your results, do you want to continue?","confirmDialogConfirmText":"Submit and see results","slideshowNavigationLabel":"Slideshow navigation"}}

Symptoms <\/strong><\/span><\/td>\n\t\t\t	Frequency<\/strong><\/span><\/td>\n\t\t<\/tr>\n\t\t
Vomiting<\/td>\n\t\t\t	69.7<\/td>\n\t\t<\/tr>\n\t\t
Altered sensorium <\/td>\n\t\t\t	69.2<\/td>\n\t\t<\/tr>\n\t\t
Anorexia<\/td>\n\t\t\t	57.1<\/td>\n\t\t<\/tr>\n\t\t
Seizures<\/td>\n\t\t\t	34.4<\/td>\n\t\t<\/tr>\n\t\t
Vision impairment<\/td>\n\t\t\t	21.2<\/td>\n\t\t<\/tr>\n\t\t
Meningeal signs<\/td>\n\t\t\t	81.8<\/td>\n\t\t<\/tr>\n\t\t
Papilledema<\/td>\n\t\t\t	48.5<\/td>\n\t\t<\/tr>\n\t\t
Cranial nerves<\/td>\n\t\t\t	\n\t\t\t 47(>=1 cranial<\/div>\n\n\t\t\t nerve palsy)<\/div>\n\t\t\t<\/td>\n\t\t<\/tr>\n\t\t
Optic atrophy<\/td>\n\t\t\t	14.6<\/td>\n\t\t<\/tr>\n\t\t
Extraneural TB<\/td>\n\t\t\t	14.1<\/td>\n\t\t<\/tr>\n\t<\/tbody>\n<\/table>\n\n <\/div>\n<\/div>\n"},"subContentId":"9b1b17eb-c831-4197-a87b-a604d7580c67","metadata":{"contentType":"Table","license":"U","title":"Untitled Table"}},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""},{"x":4.357298474945534,"y":90.71274298056156,"width":81.69934640522877,"height":6.479481641468682,"action":{"library":"H5P.AdvancedText 1.1","params":{"text":" Goyal, Vinay, et al. \u201cPractice Trends in Treating CNS TB and Outcomes at a Tertiary Care Hospital: A Cohort Study of 244 Cases.2019<\/span><\/p>\n"},"subContentId":"ee199d32-ea76-46d7-b01e-cfaf50007dfb","metadata":{"contentType":"Text","license":"U","title":"Untitled Text"}},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""}],"slideBackgroundSelector":{}},{"elements":[{"x":4.357298474945534,"y":8.639308855291576,"width":40.30501089324619,"height":10.799136069114471,"action":{"library":"H5P.AdvancedText 1.1","params":{"text":" Differential Diagnosis of TB Meningitis<\/span><\/span><\/strong><\/span><\/p>\n"},"subContentId":"7fd1dc81-a197-4646-b585-eaad24a4f411","metadata":{"contentType":"Text","license":"U","title":"Untitled Text"}},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""},{"x":5.446623093681917,"y":17.278617710583152,"width":51.19825708061002,"height":73.43412526997841,"action":{"library":"H5P.AdvancedText 1.1","params":{"text":" \n\t \n\t Partially treated bacterial meningitis<\/p>\n\t<\/li>\n\t \n\t Fungal (Cryptococcal) meningitis<\/p>\n\t<\/li>\n\t \n\t Viral meningoencephalitis<\/p>\n\t<\/li>\n\t \n\t Carcinomatous meningitis<\/p>\n\t<\/li>\n\t \n\t Neuro-sarcoidosis<\/p>\n\t<\/li>\n\t \n\t Neurosyphilis<\/p>\n\t<\/li>\n\t \n\t Uncommon: Lyme\u2019s disease, Brucellosis<\/p>\n\t<\/li>\n<\/ul>\n"},"subContentId":"a5efa0d6-63e5-4f2e-b138-20a75a29ea52","metadata":{"contentType":"Text","license":"U","title":"Untitled Text"}},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""},{"x":5.446623093681917,"y":88.55291576673866,"width":65.359477124183,"height":6.479481641468682,"action":{"library":"H5P.AdvancedText 1.1","params":{"text":" Important to rule out cryptococcal meningitis - implications with respect to steroids<\/span><\/em><\/p>\n"},"subContentId":"b9dcd3ce-4a28-4e11-9ca7-a1d7e04f01e0","metadata":{"contentType":"Text","license":"U","title":"Untitled Text"}},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""}],"slideBackgroundSelector":{}},{"elements":[{"x":4.357298474945534,"y":10.799136069114471,"width":62.091503267973856,"height":8.639308855291576,"action":{"library":"H5P.AdvancedText 1.1","params":{"text":" Clinical Presentation - CNS Tuberculoma\/abscess<\/span><\/span><\/strong><\/span><\/p>\n"},"subContentId":"12fbd60a-5780-4581-93ff-5680b796cc66","metadata":{"contentType":"Text","license":"U","title":"Untitled Text"}},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""},{"x":5.443790849673203,"y":17.312354211663067,"width":89.32461873638344,"height":71.27429805615552,"action":{"library":"H5P.AdvancedText 1.1","params":{"text":" \n\t \n\t It is less common than TBM ( about 40%) and has lower morbidity and mortality<\/p>\n\t<\/li>\n\t \n\t It can arise anywhere in brain or spinal cord<\/p>\n\t<\/li>\n\t \n\t It may present as <\/p>\n\t<\/li>\n<\/ul>\n\n a) Asymptomatic \n b) Focal seizures \n c) Mass lesion causing focal neurological deficits<\/p>\n\n \n\t \n\t Presumptive CNS tuberculoma: Any patient presenting with seizures, headache, fever or focal neurological deficits with neuroimaging features consistent with a mass lesion of inflammatory nature.<\/p>\n\t<\/li>\n<\/ul>\n"},"subContentId":"e7aaf2d1-8b91-489d-a495-022e9b6c9bd4","metadata":{"contentType":"Text","license":"U","title":"Untitled Text"}},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""},{"x":4.357298474945534,"y":84.23326133909288,"width":76.25272331154684,"height":10.799136069114471,"action":{"library":"H5P.AdvancedText 1.1","params":{"text":" Index TB Guidelines 2016; \nGoyal, Vinay, et al. \u201cPractice Trends in Treating CNS TB and Outcomes at a Tertiary Care Hospital: A Cohort Study of 244 Cases.2019<\/span><\/p>\n"},"subContentId":"9cfaad21-fc1f-493d-b199-d48e4f1b09a0","metadata":{"contentType":"Text","license":"U","title":"Untitled Text"}},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""}],"slideBackgroundSelector":{}}],"keywordListEnabled":true,"globalBackgroundSelector":{},"keywordListAlwaysShow":false,"keywordListAutoHide":false,"keywordListOpacity":90},"override":{"activeSurface":false,"hideSummarySlide":false,"summarySlideSolutionButton":true,"summarySlideRetryButton":true,"enablePrintButton":false,"social":{"showFacebookShare":false,"facebookShare":{"url":"@currentpageurl","quote":"I scored @score out of @maxScore on a task at @currentpageurl."},"showTwitterShare":false,"twitterShare":{"statement":"I scored @score out of @maxScore on a task at @currentpageurl.","url":"@currentpageurl","hashtags":"h5p, course"},"showGoogleShare":false,"googleShareUrl":"@currentpageurl"}},"l10n":{"slide":"Slide","score":"Score","yourScore":"Your Score","maxScore":"Max Score","total":"Total","totalScore":"Total Score","showSolutions":"Show solutions","retry":"Retry","exportAnswers":"Export text","hideKeywords":"Hide sidebar navigation menu","showKeywords":"Show sidebar navigation menu","fullscreen":"Fullscreen","exitFullscreen":"Exit fullscreen","prevSlide":"Previous slide","nextSlide":"Next slide","currentSlide":"Current slide","lastSlide":"Last slide","solutionModeTitle":"Exit solution mode","solutionModeText":"Solution Mode","summaryMultipleTaskText":"Multiple tasks","scoreMessage":"You achieved:","shareFacebook":"Share on Facebook","shareTwitter":"Share on Twitter","shareGoogle":"Share on Google+","summary":"Summary","solutionsButtonTitle":"Show comments","printTitle":"Print","printIngress":"How would you like to print this presentation?","printAllSlides":"Print all slides","printCurrentSlide":"Print current slide","noTitle":"No title","accessibilitySlideNavigationExplanation":"Use left and right arrow to change slide in that direction whenever canvas is selected.","accessibilityCanvasLabel":"Presentation canvas. 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CNS TB Clinical Presentation

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