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  • First line anti TB drugs

    Learning Objectives

    Enumerate the different first line anti-TB Drugs that are used and their function.

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First line drugs are the least toxic and most effective drugs that are used in first line of therapy.

 

The first-line antituberculosis drugs that form the core of treatment regimens are

 

Drugs Characteristics
Rifampicin (R) Helps in early clearance of tuberculosis bacteria from the specimen
Isoniazid (H) Most Powerful drug, that destroys all population of tuberculosis organism
Pyrazinamide (Z) Kills or stops the growth of certain populations of TB bacilli
Ethambutol (E) Prevents the growth of TB bacilli in association with other tuberculosis drugs to prevent emergence of resistant bacilli

 

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