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Adverse drug reactions should be identified<\/strong><\/span> during patient interactions at the start of treatment, with treatment supporters also involved in sensitization sessions regarding common ADRs. <\/span><\/span><\/span><\/span><\/span><\/span><\/p>\n"},"subContentId":"8dad6271-6c36-49e5-b6b8-549cb7c3231a","metadata":{"contentType":"Text","license":"U","title":"Untitled Text"}},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""},{"x":23.9880059970015,"y":50.29585798816568,"width":73.46326836581709,"height":14.792899408284024,"action":{"library":"H5P.AdvancedText 1.1","params":{"text":"

If an ADR is reported by the patient <\/span><\/strong>in the field, the N\/DDR-TBC must be immediately informed. <\/span><\/span><\/span><\/span><\/span><\/span><\/p>\n"},"metadata":{"contentType":"Text","license":"U","title":"Untitled Text"},"subContentId":"61254d71-addc-4f2c-9629-9ac2e250b957"},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""},{"x":23.9880059970015,"y":76.92307692307692,"width":73.46326836581709,"height":14.792899408284024,"action":{"library":"H5P.AdvancedText 1.1","params":{"text":"

If treatment is stopped in the field <\/strong><\/span>for any reason, N\/DDR-TBC should be notified to take appropriate actions, including reintroducing the treatment, modifying the regimen, or managing the ADR.<\/span><\/span><\/span><\/span><\/span><\/span><\/p>\n"},"metadata":{"contentType":"Text","license":"U","title":"Untitled Text"},"subContentId":"c7d9150f-e60a-4086-844c-f0fb60863670"},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""},{"x":4.497751124437781,"y":8.875739644970414,"width":13.493253373313344,"height":26.627218934911244,"action":{"library":"H5P.Shape 1.0","params":{"shape":{"fillColor":"rgb(0, 144, 255)","borderWidth":"0","borderStyle":"solid","borderColor":"rgb(0, 0, 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Common ADRs observed <\/strong><\/span>in patients treated with Pa in combination with Bdq and Lzd include peripheral neuropathy, hematological issues, visual impairment, and cardiotoxicity. <\/span><\/span><\/span><\/span><\/span><\/span><\/p>\n"},"subContentId":"d817c0c6-2a81-46c3-af5c-7d8d2071a9b5","metadata":{"contentType":"Text","license":"U","title":"Untitled Text"}},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""},{"x":23.9880059970015,"y":41.42011834319527,"width":73.46326836581709,"height":11.834319526627219,"action":{"library":"H5P.AdvancedText 1.1","params":{"text":"

Other reactions<\/strong><\/span> may include acne, nausea, vomiting, headache, increased liver enzymes, dyspepsia, rash, abdominal pain, and others.<\/span><\/span><\/span><\/span><\/span><\/span><\/p>\n"},"metadata":{"contentType":"Text","license":"U","title":"Untitled Text"},"subContentId":"73fc508e-9ad6-46d2-9ab9-c5f302e62d12"},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""},{"x":23.9880059970015,"y":68.04733727810651,"width":76.0119940029985,"height":17.75147928994083,"action":{"library":"H5P.AdvancedText 1.1","params":{"text":"

Recent safety data from four clinical trials and a paternity survey have reduced concerns regarding reproductive toxicities <\/strong><\/span>of Pa, especially in terms of male fertility, though a semen study in men undergoing treatment is ongoing to further assess this.<\/span><\/span><\/span><\/span><\/span><\/span><\/p>\n"},"metadata":{"contentType":"Text","license":"U","title":"Untitled Text"},"subContentId":"68795155-3754-49f4-854c-522ce6d5a60a"},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""},{"x":23.9880059970015,"y":90.23668639053254,"width":73.46326836581709,"height":8.875739644970414,"action":{"library":"H5P.AdvancedText 1.1","params":{"text":"

For ADRs related to Bdq, Lzd, and other drugs, refer to the Guidelines for PMDT in India \u2013 2021.<\/strong><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/p>\n"},"metadata":{"contentType":"Text","license":"U","title":"Untitled Text"},"subContentId":"fbe10bc3-6f77-4844-8b4c-625b3cea3263"},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""},{"x":4.497751124437781,"y":2.9585798816568047,"width":13.493253373313344,"height":26.627218934911244,"action":{"library":"H5P.Shape 1.0","params":{"shape":{"fillColor":"rgb(0, 144, 255)","borderWidth":"0","borderStyle":"solid","borderColor":"rgb(0, 0, 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Management of ADRs - DR-TB Treatment

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Management of ADRs - DR-TB Treatment

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