Delamanid [Dlm] Drug Dosages and Duration​

Delamanid (Dlm) is considered only for the longer oral Multi (M)/ Extensively Drug-resistant TB (XDR-TB) regimen as per the Programmatic Management of Drug-resistant TB (PMDT) guidelines.

• Formulation: Film-coated tablet with 50 mg Delamanid

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• Duration:  24 weeks

         The Optimal Background Regimen (OBR) will be continued beyond the 24 weeks of Dlm administration.

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• Dosage:
  • Adolescent (12-17 years) and adults: 100 mg orally twice daily (two tablets of 50 mg)
  • Children (6-11 years): 50 mg orally twice daily

Resources

• Guidelines for Programmatic Management of Drug-resistant Tuberculosis in India, March 2021.
• World Health Organization. The use of Delamanid in Treatment of Multidrug-resistant Tuberculosis: Interim Policy Guidance, 2016.
• Guidelines for the Use of Delamanid in the Treatment of Drug-resistant TB in India, 2018.
• Consolidated Guidelines on Tuberculosis, Module 4- Treatment: Drug-resistant TB Treatment.

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