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Critical Concentration for PZA Drugs Recommended for the Treatment of DS- TB

 

Anti TB drugs

CC (ug/ml) for DST medium

Pyrazinamide

100μg/mL

 

 

 

Reconstitution of PZA Lyophilized Drugs (Drug stock preparation)

Reconstitute the PZA drug vial with 2.5 ml sterile distilled/ deionized water to make a stock solution of 8000 μg/ml. Failure to use the appropriate volume will invalidate these tests.

Drug lyophilised

 

 

Concentration of

reconstituted agent

μg/mL*

 

Volume added

to each MGIT tube

 

Final concentration

in MGIT tubes

 

Pyrazinamide (PZA)

8000 μg/ml

100 μl

100μg/mL

 

                                                   *PZA must be reconstituted using 2.5 mL sterile/deionized water to achieve the concentration indicated.

Resource

Mycobacteriology Laboratory Manual      

Assessment

Question​

Answer 1​

Answer 2​

Answer 3​

Answer 4​

Correct answer​

Correct explanation​

Page id​

Part of Pre-test​

Part of Post-te

Which of the following is the Critical Concentration for PZA drugs recommended for the treatment of DS- TB?

 

 100μg/mL 10μg/mL 1000μg/mL 800μg/mL Answer 1 Critical Concentration for PZA drugs recommended for the treatment of DS- TB is:100μg/mL.      

 

 

 

 

 

 

 

 

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