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Quality Control of DST is critical to ensure the test is functioning properly so that reliable results can be interpreted. ​

Steps in Quality Control in DST result interpretation include: 

1. SIRE/ Second- line and PZA QC

  • Carefully entering the tubes into MGIT 960​
  • Carefully scanning the DST set carrier into the BACTEC MGIT 960 instrument.

 

2. Interpretation of results
 

  • The time period to interpret results is crucial. Interpret between 4–13 days for first and second-line drugs and 4-21 days for PZA. ​
  • Results should read susceptible for all drugs.
  • If proper results are not obtained, repeat the test.

 

3. First and Second- line drugs and PZA QC Records​
 

  • Record lot numbers of MGIT 960 tubes, drugs and drug supplements. ​
  • Record QC results.
  • Maintain records for a minimum of five years.

Resource

GLI Practical Guide to TB Laboratory Strengthening

Assessment

Question​

 

 

Answer 1​

 

 

Answer 2

 

 

Answer 3

 

 

Answer 4

 

 

Correct answer​

 

 

Correct explanation​

 

 

Page id​

 

 

Part of Pre-test​

 

 

Part of Post-test​

 

 

Quality control in DST result interpretation includes which of the following?

 

 

Interpret the results between 4–13 days for first and second-line drugs and 4-21 days for PZA. ​

 

 

Ensure proper reconstitution of lyophilized drugs.

 

 

Use calibrated pipette.

 

 

 Use control strains and reagents,

1

 

 

Interpret the results between 4–13 days for first and second-line drugs and 4-21 days for PZA. ​

 

 

 

YES

 

 

YES

 

 

 

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