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Constituents of Patient-wise Boxes [PWB] of Longer Oral M/XDR-TB Regimen
Learning ObjectivesPWB for longer oral M/XDR regimen.
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Standard monthly Drug-resistant TB (DR-TB) Patient-wise Boxes (PWBs) are utilized for patients initiated on a longer Multi/ Extensively Drug-resistant TB (M/XDR-TB) regimen. These PWBs are constituted either at the National TB Elimination Programme (NTEP) State Drug Store (SDS) level or District Drug Store Level (DDS). Child-friendly formulations of second-line anti-TB drugs are also available.
The constituents of the monthly standard patient-wise boxes (drugs, drug strength and weight-band wise medicinal formulations) are provided in the table below:
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Standard PWB*
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Continue till complete treatment
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|---|---|---|---|---|---|
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Drugs
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Strength
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16-29 kg
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30-46 kg
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48-70 kg
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>70 kg
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Tab. Levofloxacin
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250/ 500 mg
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250 mg *30 tab
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500 mg *30 tab + 250 mg *30 tab
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500 mg *60 tab
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500 mg *60 tab
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Tab. Linezolid#
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600 mg
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600 mg *30 tab#
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600 mg *30 tab
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600 mg *30 tab
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600 mg *30 tab
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Tab. Clofazimine
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50/ 100 mg
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50 mg *30 tab
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100 mg *30 tab
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100 mg *30 tab
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100 mg *60 tab
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Tab. Cycloserine
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250 mg
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250 mg *30 tab
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250 mg *60 tab
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250 mg *90 tab
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250 mg *120 tab
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Tab. Pyridoxine
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50/ 100 mg
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50 mg *30 tab
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100 mg *30 tab
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100 mg *30 tab
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100 mg *30 tab
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Bedaquiline bottle
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100 mg
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1 Jar (Jar of 188 tablets for full course)
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*No separate box for Intensive Phase (IP) and Continuation Phase (CP).
# Tab. linezolid is available in 600 mg only. When prescribed with a modified dose of 300 mg OD, the patient should be advised to divide the pill in half, consume half of the pill and throw the remaining half of the pill in the drain.
Longer oral M/XDR-TB regimen duration: 18-20 months
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