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Patients must be actively screened for any early development of Linezolid induced adverse events especially Myelosuppression and neuropathy. This is done more frequently in patients of higher risk groups, such as:<\/p>\n\n

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Patients with co-morbidities like Diabetes mellitus, PLHIV, History of substance abuse, Hypothyroidism, and abnormal baseline electrolytes.
\n <\/p>\n\n

Low BMI < 18.5
\n <\/p>\n\n

Pre-existing anemia Hb <8.00 (gm\/dl)
\n <\/p>\n\n

Nutritional deficiencies
\n <\/p>\n\n

Patients complaining of vomiting for more than a week.
\n <\/p>\n\n

Lack of gain in appetite or weight or weight loss.<\/p>\n"},"subContentId":"43a03f73-7854-4b5e-9ff1-9bde1eb09064","metadata":{"contentType":"Text","license":"U","title":"Untitled Text"}},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""},{"x":6.5359477124183005,"y":17.204301075268816,"width":8.387799564270153,"height":80.64516129032258,"action":{"library":"H5P.Image 1.1","params":{"decorative":false,"contentName":"Image","expandImage":"Expand Image","minimizeImage":"Minimize Image","file":{"path":"images\/file-672d05f15c31f.png","mime":"image\/png","copyright":{"license":"U"},"width":184,"height":910}},"subContentId":"d1d772de-372c-4894-9dfe-19628ec290e6","metadata":{"contentType":"Image","license":"U","title":"Untitled 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Any of the following may prompt detailed assessment for the ADRs:<\/strong><\/p>\n\n

<\/p>\n\n

<\/p>\n"},"subContentId":"86b144e2-ae83-4876-b78d-5873a25c43c4","metadata":{"contentType":"Text","license":"U","title":"Untitled Text"}},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""},{"x":62.2004357298475,"y":16.344086021505376,"width":37.145969498910674,"height":80.21505376344085,"action":{"library":"H5P.AdvancedText 1.1","params":{"text":"

\n\t
Slipping off of footwear without knowledge
\n\t <\/li>\n\t
Inability to place his soles on the ground.
\n\t <\/li>\n\t
Frequent sores or ulcers on the feet.
\n\t <\/li>\n\t
Diminution in the vision
\n\t <\/li>\n\t
>10% drop in Hemoglobin from baseline or reduction in the TLC or Platelet count to Grade 3 or 4.<\/li>\n<\/ul>\n"},"subContentId":"7b646f84-dd7a-41f9-a910-584e321dd109","metadata":{"contentType":"Text","license":"U","title":"Untitled Text"}},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""},{"x":11.764705882352942,"y":14.193548387096772,"width":37.472766884531595,"height":85.80645161290322,"action":{"library":"H5P.AdvancedText 1.1","params":{"text":"
\n\t
Numbness , Burning ,prickly ( pins and needles) feelings in the feet
\n\t <\/li>\n\t
Feel hurt when bed covers touch the skin.
\n\t <\/li>\n\t
Craps in the muscles of the leg or muscle weakness.
\n\t <\/li>\n\t
Inability to distinguish hot or cold water while bathing
\n\t <\/li>\n\t
Worsening of symptoms at night or increase in leg pain while walking<\/li>\n<\/ul>\n"},"subContentId":"fba92a95-300f-40a2-81f5-8d821b43e046","metadata":{"contentType":"Text","license":"U","title":"Untitled Text"}},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""},{"x":49.94553376906318,"y":15.618279569892474,"width":0.32679738562091504,"height":79.78494623655914,"action":{"library":"H5P.Shape 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Screening of patients on BPaLM regimen for Linezolid toxicity

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Screening of patients on BPaLM regimen for Linezolid toxicity

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