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Blood sugar levels<\/strong><\/span> may be difficult to control in patients with MDR\/RR-TB and diabetes, and require insulin to gain adequate blood sugar control during treatment. <\/span><\/span><\/span><\/p>\n"},"subContentId":"03c218ce-d619-43ce-86bc-cc9b08254a67","metadata":{"contentType":"Text","license":"U","title":"Untitled Text"}},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""},{"x":4.497751124437781,"y":5.903284023668639,"width":10.494752623688155,"height":20.710059171597635,"action":{"library":"H5P.Shape 1.0","params":{"shape":{"fillColor":"rgb(0, 132, 252)","borderWidth":"0","borderStyle":"solid","borderColor":"#000","borderRadius":"0"},"type":"circle","line":{"borderColor":"#000000","borderWidth":"1","borderStyle":"solid"}},"subContentId":"d9a2f7ff-7c7d-47be-b3ba-6ae3014e24df","metadata":{"contentType":"Shapes","license":"U"}},"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false},{"x":6.746626686656672,"y":11.515355029585798,"width":10.494752623688155,"height":20.710059171597635,"action":{"library":"H5P.Image 1.1","params":{"decorative":false,"contentName":"Image","expandImage":"Expand Image","minimizeImage":"Minimize Image","file":{"path":"images\/file-672b6d07c3f46.png","mime":"image\/png","copyright":{"license":"U"},"width":512,"height":512}},"subContentId":"308f9bd9-726e-4aaf-9354-446e642e6dec","metadata":{"contentType":"Image","license":"U","title":"Untitled Image"}},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""},{"x":17.09145427286357,"y":44.37869822485207,"width":34.48275862068966,"height":23.668639053254438,"action":{"library":"H5P.AdvancedText 1.1","params":{"text":"

Patients with diabetes<\/strong><\/span> are also at increased risk of peripheral neuropathies, which may be further exacerbated following exposure to Lzd and Hh. <\/span><\/span><\/span><\/p>\n"},"metadata":{"contentType":"Text","license":"U","title":"Untitled Text"},"subContentId":"02823201-f1d6-415a-a1d3-ff968f88b3ff"},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""},{"x":17.24137931034483,"y":73.96449704142012,"width":34.48275862068966,"height":23.37278106508876,"action":{"library":"H5P.AdvancedText 1.1","params":{"text":"

These patients must be counselled to report symptoms<\/strong><\/span> of peripheral neuropathies early because such symptoms may necessitate a change in regimen <\/span><\/span><\/span><\/p>\n"},"metadata":{"contentType":"Text","license":"U","title":"Untitled Text"},"subContentId":"bf5c45a8-f209-4e6e-82a3-771b049d9f9e"},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""},{"x":4.497751124437781,"y":41.42011834319527,"width":10.494752623688155,"height":20.710059171597635,"action":{"library":"H5P.Shape 1.0","params":{"shape":{"fillColor":"rgb(0, 132, 252)","borderWidth":"0","borderStyle":"solid","borderColor":"#000","borderRadius":"0"},"type":"circle","line":{"borderColor":"#000000","borderWidth":"1","borderStyle":"solid"}},"metadata":{"contentType":"Shapes","license":"U"},"subContentId":"9ff629d6-bf68-44e0-82c2-7e1d7968c6f1"},"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false},{"x":4.497751124437781,"y":71.00591715976331,"width":10.494752623688155,"height":20.710059171597635,"action":{"library":"H5P.Shape 1.0","params":{"shape":{"fillColor":"rgb(0, 132, 252)","borderWidth":"0","borderStyle":"solid","borderColor":"#000","borderRadius":"0"},"type":"circle","line":{"borderColor":"#000000","borderWidth":"1","borderStyle":"solid"}},"metadata":{"contentType":"Shapes","license":"U"},"subContentId":"f7fef995-ed0f-42f4-b917-8d7ff8ba80a1"},"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false},{"x":7.496251874062969,"y":78.40236686390533,"width":8.995502248875562,"height":17.75147928994083,"action":{"library":"H5P.Image 1.1","params":{"decorative":false,"contentName":"Image","expandImage":"Expand Image","minimizeImage":"Minimize Image","file":{"path":"images\/file-672b6e70c2e00.png","mime":"image\/png","copyright":{"license":"U"},"width":512,"height":512}},"subContentId":"6c7a9542-b52c-4187-a103-5e1bf556a8a9","metadata":{"contentType":"Image","license":"U","title":"Untitled Image"}},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""},{"x":53.523238380809595,"y":5.9171597633136095,"width":10.494752623688155,"height":20.710059171597635,"action":{"library":"H5P.Shape 1.0","params":{"shape":{"fillColor":"rgb(0, 132, 252)","borderWidth":"0","borderStyle":"solid","borderColor":"#000","borderRadius":"0"},"type":"circle","line":{"borderColor":"#000000","borderWidth":"1","borderStyle":"solid"}},"metadata":{"contentType":"Shapes","license":"U"},"subContentId":"a59a9399-3242-439c-8030-158ab58b8d2c"},"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false},{"x":53.673163418290855,"y":41.42011834319527,"width":10.494752623688155,"height":20.710059171597635,"action":{"library":"H5P.Shape 1.0","params":{"shape":{"fillColor":"rgb(0, 132, 252)","borderWidth":"0","borderStyle":"solid","borderColor":"#000","borderRadius":"0"},"type":"circle","line":{"borderColor":"#000000","borderWidth":"1","borderStyle":"solid"}},"metadata":{"contentType":"Shapes","license":"U"},"subContentId":"942b60a8-b97e-4572-89c7-05958b8e4ba2"},"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false},{"x":53.673163418290855,"y":71.00591715976331,"width":10.494752623688155,"height":20.710059171597635,"action":{"library":"H5P.Shape 1.0","params":{"shape":{"fillColor":"rgb(0, 132, 252)","borderWidth":"0","borderStyle":"solid","borderColor":"#000","borderRadius":"0"},"type":"circle","line":{"borderColor":"#000000","borderWidth":"1","borderStyle":"solid"}},"metadata":{"contentType":"Shapes","license":"U"},"subContentId":"14fd41eb-038a-4546-a0d1-944bba3a934d"},"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false},{"x":1.4992503748125938,"y":44.37869822485207,"width":17.991004497751124,"height":28.106508875739646,"action":{"library":"H5P.Image 1.1","params":{"decorative":false,"contentName":"Image","expandImage":"Expand Image","minimizeImage":"Minimize Image","file":{"path":"images\/file-672b6fc6d2723.png","mime":"image\/png","copyright":{"license":"U"},"width":337,"height":267}},"subContentId":"b2d0c318-ff71-48ee-b5ed-145b629d6ed3","metadata":{"contentType":"Image","license":"U","title":"Untitled Image"}},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""},{"x":64.46776611694153,"y":7.969674556213017,"width":34.48275862068966,"height":32.544378698224854,"action":{"library":"H5P.AdvancedText 1.1","params":{"text":"

The concomitant use of metformin at high doses and Lzd may increase the risk of lactic acidosis<\/strong><\/span>. Also, the long-term use of Lzd, Hn <\/span><\/span><\/span><\/span>and cycloserine (Cs) in patients with diabetes can lead to an increased risk of peripheral neuritis. <\/span><\/span><\/span><\/p>\n"},"metadata":{"contentType":"Text","license":"U","title":"Untitled Text"},"subContentId":"4eb0c697-9aa7-4c40-9bae-845fc1273242"},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""},{"x":64.46776611694153,"y":44.23994082840237,"width":34.48275862068966,"height":32.544378698224854,"action":{"library":"H5P.AdvancedText 1.1","params":{"text":"

Baseline optic neuropathy or retinopathy or maculopathy may worsen after Lzd use; hence, eye evaluation is recommended<\/strong><\/span> before and during treatment. <\/span><\/span><\/span><\/p>\n"},"metadata":{"contentType":"Text","license":"U","title":"Untitled Text"},"subContentId":"f39554a4-19d8-47b5-9357-effdf673913f"},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""},{"x":64.46776611694153,"y":73.81656804733728,"width":32.98350824587706,"height":20.710059171597635,"action":{"library":"H5P.AdvancedText 1.1","params":{"text":"

Patients with DR-TB and diabetes may need close follow-up and support<\/strong><\/span>, with quick identification of drug\u2013drug interactions and adverse events.<\/span><\/span><\/span><\/p>\n"},"metadata":{"contentType":"Text","license":"U","title":"Untitled Text"},"subContentId":"93ec819a-cf00-4147-9e43-c21caea2cedb"},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""},{"x":53.823088455772115,"y":47.92899408284024,"width":10.494752623688155,"height":20.710059171597635,"action":{"library":"H5P.Image 1.1","params":{"decorative":false,"contentName":"Image","expandImage":"Expand Image","minimizeImage":"Minimize Image","file":{"path":"images\/file-672b7127f2374.png","mime":"image\/png","copyright":{"license":"U"},"width":512,"height":512}},"subContentId":"1f6ff78a-f9d1-4719-9922-7a84b97f3e58","metadata":{"contentType":"Image","license":"U","title":"Untitled Image"}},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""},{"x":53.823088455772115,"y":14.497041420118343,"width":9.745127436281859,"height":19.23076923076923,"action":{"library":"H5P.Image 1.1","params":{"decorative":false,"contentName":"Image","expandImage":"Expand Image","minimizeImage":"Minimize Image","file":{"path":"images\/file-672b715e87c72.png","mime":"image\/png","copyright":{"license":"U"},"width":512,"height":512}},"subContentId":"2979e50d-114a-4f73-925f-db373258b5e4","metadata":{"contentType":"Image","license":"U","title":"Untitled Image"}},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""},{"x":54.42278860569715,"y":76.92307692307692,"width":8.995502248875562,"height":17.75147928994083,"action":{"library":"H5P.Image 1.1","params":{"decorative":false,"contentName":"Image","expandImage":"Expand Image","minimizeImage":"Minimize Image","file":{"path":"images\/file-672b71c2df3a8.png","mime":"image\/png","copyright":{"license":"U"},"width":512,"height":512}},"subContentId":"1ff22289-efbd-4795-88e0-549eff20d3ad","metadata":{"contentType":"Image","license":"U","title":"Untitled Image"}},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""}],"slideBackgroundSelector":{}}],"keywordListEnabled":true,"globalBackgroundSelector":{},"keywordListAlwaysShow":false,"keywordListAutoHide":false,"keywordListOpacity":90},"override":{"activeSurface":false,"hideSummarySlide":false,"summarySlideSolutionButton":true,"summarySlideRetryButton":true,"enablePrintButton":false,"social":{"showFacebookShare":false,"facebookShare":{"url":"@currentpageurl","quote":"I scored @score out of @maxScore on a task at @currentpageurl."},"showTwitterShare":false,"twitterShare":{"statement":"I scored @score out of @maxScore on a task at @currentpageurl.","url":"@currentpageurl","hashtags":"h5p, course"},"showGoogleShare":false,"googleShareUrl":"@currentpageurl"}},"l10n":{"slide":"Slide","score":"Score","yourScore":"Your Score","maxScore":"Max Score","total":"Total","totalScore":"Total Score","showSolutions":"Show solutions","retry":"Retry","exportAnswers":"Export text","hideKeywords":"Hide sidebar navigation menu","showKeywords":"Show sidebar navigation menu","fullscreen":"Fullscreen","exitFullscreen":"Exit fullscreen","prevSlide":"Previous slide","nextSlide":"Next slide","currentSlide":"Current slide","lastSlide":"Last slide","solutionModeTitle":"Exit solution mode","solutionModeText":"Solution Mode","summaryMultipleTaskText":"Multiple tasks","scoreMessage":"You achieved:","shareFacebook":"Share on Facebook","shareTwitter":"Share on Twitter","shareGoogle":"Share on Google+","summary":"Summary","solutionsButtonTitle":"Show comments","printTitle":"Print","printIngress":"How would you like to print this presentation?","printAllSlides":"Print all slides","printCurrentSlide":"Print current slide","noTitle":"No title","accessibilitySlideNavigationExplanation":"Use left and right arrow to change slide in that direction whenever canvas is selected.","accessibilityCanvasLabel":"Presentation canvas. 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Management DR-TB in Special Situations - People with Diabetes Mellitus

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Management DR-TB in Special Situations - People with Diabetes Mellitus

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