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Treatment Regimen for DSTB - Pediatrics
Learning ObjectivesTreatment Regimen for DSTB - Pediatrics
Intensive Phase (IP)
Consists of eight weeks (56 doses) of HRZ in daily dosages as per weight of patient.
Ethambutol (E) is given separately for children to monitor ophthalmic side effects.
Continuous Phase (CP)
Consists of 16 weeks (112 doses) of HRE in daily dosages as per the weight of the patient.
In Pediatric, there are six weight bands’s as shown in the table below. The table also indicates the number of FDC tablets that has to be consumed in each weight band
|
Weight Band category
|
Fixed-Dose Combinations (FDCs) |
|
|
Intensive phase (IP) (HRZE - 75/150/400/275) |
Continuation phase (CP) (HRE - 75/150/275) |
|
|
4-7 kgs |
1 | 1 |
|
8-11 kgs |
2 | 2 |
|
12-15 kgs |
3 | 3 |
|
16-24 Kgs |
4 | 4 |
|
25-29 Kgs |
3 + 1A | 3 + 1A |
|
30-39 Kgs |
2 + 2A | 2 + 2A |
Regular monthly follow-up of the paediatric patient needs to be done and if the patient weight crosses the range of the weight band during the treatment, then the weight band of the patient should be changed immediately.
Children above 39 kg shall usually be adolescents, the drug dosage requirement for them would be similar to adults
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