{"presentation":{"slides":[{"elements":[{"x":7.625272331154684,"y":6.451612903225806,"width":14.161220043572985,"height":6.451612903225806,"action":{"library":"H5P.AdvancedText 1.1","params":{"text":"

PTE Objective<\/strong><\/span><\/p>\n\n

\n<\/ul>\n"},"subContentId":"ab62092d-08d6-46db-b2cd-0994356d1817","metadata":{"contentType":"Text","license":"U","title":"Untitled Text"}},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""},{"x":7.625272331154684,"y":38.70967741935483,"width":39.97821350762527,"height":6.451612903225806,"action":{"library":"H5P.AdvancedText 1.1","params":{"text":"
PTE is essential to identify:<\/strong><\/span><\/p>\n\n
<\/p>\n"},"subContentId":"1e82835a-9da2-49bf-83aa-629c99f3bc32","metadata":{"contentType":"Text","license":"U","title":"Untitled Text"}},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""},{"x":14.161220043572985,"y":17.204301075268816,"width":82.78867102396515,"height":19.354838709677416,"action":{"library":"H5P.AdvancedText 1.1","params":{"text":"
Drugs used for the treatment of drug-resistant TB have significant adverse effects. Hence, there is a need for PTE to rule out any underlying condition at the baseline, like co-morbid conditions, radiological abnormalities, Electrocardiogram (ECG) changes, or biochemical derangements. <\/p>\n"},"subContentId":"2e461daa-0501-42f8-aed0-449407f89c9b","metadata":{"contentType":"Text","license":"U","title":"Untitled Text"}},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""},{"x":4.357298474945534,"y":15.053763440860214,"width":8.714596949891067,"height":17.204301075268816,"action":{"library":"H5P.Image 1.1","params":{"decorative":false,"contentName":"Image","expandImage":"Expand Image","minimizeImage":"Minimize Image","file":{"path":"images\/file-672bc6be12bd5.png","mime":"image\/png","copyright":{"license":"U"},"width":512,"height":512}},"subContentId":"7ddd56a3-f895-47bf-90a0-3ab9ccc80bb9","metadata":{"contentType":"Image","license":"U","title":"Untitled Image"}},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""},{"x":17.429193899782135,"y":49.46236559139785,"width":55.55555555555556,"height":47.31182795698924,"action":{"library":"H5P.AdvancedText 1.1","params":{"text":"
The patient's eligibility for initiation of a particular regimen<\/p>\n\n
<\/p>\n\n
Patients who require special attention during treatment<\/p>\n\n
<\/p>\n\n
Regimen modifications from the beginning of treatment<\/p>\n"},"subContentId":"42b44217-7163-4205-9571-45b7685c297a","metadata":{"contentType":"Text","license":"U","title":"Untitled Text"}},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""},{"x":10.893246187363834,"y":47.31182795698924,"width":4.357298474945534,"height":8.602150537634408,"action":{"library":"H5P.Shape 1.0","params":{"shape":{"fillColor":"rgb(76, 193, 239)","borderWidth":"0","borderStyle":"solid","borderColor":"#000","borderRadius":"0"},"type":"rectangle","line":{"borderColor":"#000000","borderWidth":"1","borderStyle":"solid"}},"subContentId":"2ae8ae6d-a1fc-49a5-9274-85eadfff8ad9","metadata":{"contentType":"Shapes","license":"U"}},"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false},{"x":10.893246187363834,"y":64.51612903225806,"width":4.357298474945534,"height":8.602150537634408,"action":{"library":"H5P.Shape 1.0","params":{"shape":{"fillColor":"rgb(76, 193, 239)","borderWidth":"0","borderStyle":"solid","borderColor":"#000","borderRadius":"0"},"type":"rectangle","line":{"borderColor":"#000000","borderWidth":"1","borderStyle":"solid"}},"metadata":{"contentType":"Shapes","license":"U"},"subContentId":"ddcf0621-29d9-4953-95fc-c3a9c04e9cfa"},"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false},{"x":10.893246187363834,"y":81.07526881720429,"width":4.357298474945534,"height":8.602150537634408,"action":{"library":"H5P.Shape 1.0","params":{"shape":{"fillColor":"rgb(76, 193, 239)","borderWidth":"0","borderStyle":"solid","borderColor":"#000","borderRadius":"0"},"type":"rectangle","line":{"borderColor":"#000000","borderWidth":"1","borderStyle":"solid"}},"metadata":{"contentType":"Shapes","license":"U"},"subContentId":"92c908e4-5a11-4b31-9be9-6fc6085ddb95"},"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false},{"x":13.071895424836603,"y":47.251397849462364,"width":38.12636165577342,"height":0.8602150537634408,"action":{"library":"H5P.Shape 1.0","params":{"line":{"borderWidth":"3","borderStyle":"solid","borderColor":"rgb(76, 193, 239)"},"type":"horizontal-line","shape":{"fillColor":"#ffffff","borderColor":"#000000","borderWidth":"0","borderStyle":"solid","borderRadius":"0"}},"subContentId":"bb75475d-4630-45b0-bab6-87fd84b67d99","metadata":{"contentType":"Shapes","license":"U"}},"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false},{"x":13.071895424836601,"y":64.51612903225806,"width":38.12636165577342,"height":0.8602150537634408,"action":{"library":"H5P.Shape 1.0","params":{"line":{"borderWidth":"3","borderStyle":"solid","borderColor":"rgb(76, 193, 239)"},"type":"horizontal-line","shape":{"fillColor":"#ffffff","borderColor":"#000000","borderWidth":"0","borderStyle":"solid","borderRadius":"0"}},"metadata":{"contentType":"Shapes","license":"U"},"subContentId":"a8e4631f-d3ad-49b0-a0dc-2d0f15fc03bc"},"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false},{"x":13.071895424836601,"y":81.07526881720429,"width":38.12636165577342,"height":0.8602150537634408,"action":{"library":"H5P.Shape 1.0","params":{"line":{"borderWidth":"3","borderStyle":"solid","borderColor":"rgb(76, 193, 239)"},"type":"horizontal-line","shape":{"fillColor":"#ffffff","borderColor":"#000000","borderWidth":"0","borderStyle":"solid","borderRadius":"0"}},"metadata":{"contentType":"Shapes","license":"U"},"subContentId":"aec1b221-8102-4685-860c-6dedcfdbd500"},"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false},{"x":11.982570806100219,"y":49.46236559139785,"width":3.2679738562091503,"height":6.451612903225806,"action":{"library":"H5P.AdvancedText 1.1","params":{"text":"
A.<\/strong><\/span><\/p>\n"},"subContentId":"f1a739cc-e239-4b78-b2b6-9211c0976ac8","metadata":{"contentType":"Text","license":"U","title":"Untitled Text"}},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""},{"x":11.982570806100219,"y":66.66666666666666,"width":3.2679738562091503,"height":6.451612903225806,"action":{"library":"H5P.AdvancedText 1.1","params":{"text":"
B.<\/strong><\/span><\/p>\n"},"metadata":{"contentType":"Text","license":"U","title":"Untitled Text"},"subContentId":"4b87ba6c-0145-4bb0-96de-41a6870c7484"},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""},{"x":11.982570806100219,"y":83.87096774193547,"width":3.2679738562091503,"height":6.451612903225806,"action":{"library":"H5P.AdvancedText 1.1","params":{"text":"
C.<\/strong><\/span><\/p>\n"},"metadata":{"contentType":"Text","license":"U","title":"Untitled Text"},"subContentId":"cac846a0-02a6-469b-a1f0-1cf46aff20ec"},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""}],"slideBackgroundSelector":{}},{"elements":[{"x":17.429193899782135,"y":12.903225806451612,"width":80.61002178649238,"height":81.72043010752688,"action":{"library":"H5P.AdvancedText 1.1","params":{"text":"
\n\t
In the majority of Multidrug-resistant (MDR)\/ Rifampicin-resistant Tuberculosis (RR-TB) patients, PTE can be done on an outpatient basis<\/strong>.<\/span>
\n\t <\/li>\n\t
The District TB Officer (DTO) and Medical Officer of the TB Unit (MO-TU) can arrange for PTE at the Nodal and District DR-TB Centre (N\/DDR-TBC) or at the sub-district level health facility, wherever feasible.
\n\t <\/li>\n\t
No additional investigations are required for H Mono\/ Poly DR-TB patients unless clinically indicated.
\n\t <\/li>\n\t
The PTE carried out at the time of treatment initiation can be considered valid for 1 month<\/strong><\/span> from the date of the test result and the patient can be re-initiated on a subsequent regimen considering the previously conducted PTEs.
\n\t <\/li>\n<\/ul>\n"},"subContentId":"cdaa9c73-ab4a-4873-8bc0-3d73dc4bb847","metadata":{"contentType":"Text","license":"U","title":"Untitled Text"}},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""},{"x":4.357298474945534,"y":4.301075268817204,"width":19.607843137254903,"height":6.451612903225806,"action":{"library":"H5P.AdvancedText 1.1","params":{"text":"
Important Points<\/strong><\/span><\/span><\/p>\n"},"subContentId":"66fac8a9-446d-43b8-a27e-300bdda650ee","metadata":{"contentType":"Text","license":"U","title":"Untitled Text"}},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""},{"x":5.446623093681917,"y":15.053763440860214,"width":9.803921568627452,"height":19.354838709677416,"action":{"library":"H5P.Shape 1.0","params":{"shape":{"fillColor":"rgb(162, 185, 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1.1","params":{"decorative":false,"contentName":"Image","expandImage":"Expand Image","minimizeImage":"Minimize Image","file":{"path":"images\/file-672bd073b1c87.png","mime":"image\/png","copyright":{"license":"U"},"width":500,"height":500}},"subContentId":"8f5c8efc-04c1-4dd0-8740-abcde66008da","metadata":{"contentType":"Image","license":"U","title":"Untitled Image"}},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""},{"x":6.5359477124183005,"y":68.81720430107526,"width":8.169934640522875,"height":16.129032258064516,"action":{"library":"H5P.Image 1.1","params":{"decorative":false,"contentName":"Image","expandImage":"Expand Image","minimizeImage":"Minimize Image","file":{"path":"images\/file-672bd15e68268.png","mime":"image\/png","copyright":{"license":"U"},"width":512,"height":512}},"subContentId":"bc3f0b8c-eed3-4295-a5ee-2542c6fc717d","metadata":{"contentType":"Image","license":"U","title":"Untitled Image"}},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""},{"x":91.83006535947713,"y":83.87096774193547,"width":8.169934640522875,"height":16.129032258064516,"action":{"library":"H5P.Image 1.1","params":{"decorative":false,"contentName":"Image","expandImage":"Expand Image","minimizeImage":"Minimize Image","file":{"path":"images\/file-672bd4f10cad5.png","mime":"image\/png","copyright":{"license":"U"},"width":512,"height":512}},"subContentId":"fd5ba3e0-72a2-40c6-9d29-a9e40465d366","metadata":{"contentType":"Image","license":"U","title":"Untitled Image"}},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""}],"slideBackgroundSelector":{}},{"elements":[{"x":16.338126361655775,"y":6.438172043010752,"width":79.520697167756,"height":86.02150537634408,"action":{"library":"H5P.AdvancedText 1.1","params":{"text":"
\n\t
Active Drug Safety Management and Monitoring (aDSM)<\/strong><\/span> treatment initiation forms are required to be completed for all DR-TB patients at the time of initiation of each new episode of treatment.
\n\t <\/li>\n\t
PTE should include a thorough clinical evaluation by a physician and expert consultation as per the need.
\n\t <\/li>\n\t
Laboratory-based tests should be performed based on the drugs used in the treatment regimen.
\n\t <\/li>\n\t
Pre-treatment evaluation should be made available free of charge<\/strong><\/span> to the patient.\u200b<\/li>\n<\/ul>\n"},"subContentId":"2d785fec-a53f-4899-b4e6-4f138c337e31","metadata":{"contentType":"Text","license":"U","title":"Untitled Text"}},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""},{"x":4.357298474945534,"y":8.602150537634408,"width":9.803921568627452,"height":19.354838709677416,"action":{"library":"H5P.Shape 1.0","params":{"shape":{"fillColor":"rgb(162, 185, 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0.497)","borderWidth":"2","borderStyle":"solid","borderColor":"#000","borderRadius":"0"},"type":"rectangle","line":{"borderColor":"#000000","borderWidth":"1","borderStyle":"solid"}},"subContentId":"f7a8394c-d428-41c7-93d1-2e0be25c8ab8","metadata":{"contentType":"Shapes","license":"U"}},"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false},{"x":11.982570806100219,"y":92.47311827956989,"width":70.04357298474946,"height":5.183585313174946,"action":{"library":"H5P.AdvancedText 1.1","params":{"text":"
Table: Pre-treatment (PTE) for MDR\/RR-TB patients<\/p>\n"},"subContentId":"7d7b5a18-0b94-445e-8da2-dfe4349b74bf","metadata":{"contentType":"Text","license":"U","title":"Untitled Text"}},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""},{"x":7.625272331154684,"y":12.903225806451612,"width":39.97821350762527,"height":79.56989247311827,"action":{"library":"H5P.AdvancedText 1.1","params":{"text":"
\n\t
History and physical examination (including previous drug use, alcohol\/ substance abuse, family planning methods etc.) <\/li>\n\t
Previous history of ATT taken, especially Bdq, Pa, Dlm and Lzd (defined as more than one month exposure)<\/li>\n\t
A thorough clinical examination: Assess nutritional status [Height (m), Weight (kg), BMI]<\/li>\n\t
Neurological evaluation, if required<\/li>\n\t
Ophthalmic evaluation, visual acuity, and color vision test<\/li>\n<\/ul>\n"},"subContentId":"07781bc6-254c-42c1-a557-ba8eb18a93d6","metadata":{"contentType":"Text","license":"U","title":"Untitled Text"}},"alwaysDisplayComments":false,"backgroundOpacity":0,"displayAsButton":false,"buttonSize":"big","goToSlideType":"specified","invisible":false,"solution":""},{"x":53.37690631808279,"y":12.903225806451612,"width":39.97821350762527,"height":75.26881720430107,"action":{"library":"H5P.AdvancedText 1.1","params":{"text":"
\n\t
Random blood sugar (RBS) <\/li>\n\t
HIV testing following counselling <\/li>\n\t
Complete blood count (Hb, TLC, DLC, platelet count)<\/li>\n\t
Liver function tests# Serum electrolytes (Na, K, Mg, Ca)<\/li>\n\t
Urine pregnancy test (in women of reproductive age group)<\/li>\n\t
Chest X-ray<\/li>\n\t
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MPW: DR-TB Treatment and care

Target Audience

Drug-Resistant Tuberculosis [DR-TB]

Screening for DR-TB

Types of Drug Resistance Tuberculosis -DRTB

DR-TB Treatment Regimens

DR-TB Treatment – Patient Flow

Pre-treatment Evaluation [PTE] of DR-TB Patients​

ADRs to Second Line Treatment

Pre-treatment Evaluation [PTE] of DR-TB Patients